Rat Anti-Mouse T-cell Immunoglobulin Mucin-2 (TIM-2)

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Cat-Nr.103-M275
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#5B23)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant TIM-2. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Antigenmouse recombinant protein of TIM-2
ApplicationWB, IHC (P)
SynonymsTimd2; G9D3; Tim2; TIM-2; C78111; AA816106; AU019358; AU019662
DescriptionTIM-2 is a type I membrane protein and is a member of the TIM protein family. TIM-2 has an immunoglobulin variable region-like domain followed by a mucin-like domain in its extracellular region.This protein family is characterized by their conserved immunoglobulin and mucin domains, as well as by their expression on activated T cells. TIM-2 is a receptor for Semaphorin 4A, which is expressed on dendritic cells and B cells. Semaphorin 4A has been shown to enhance T cell activation.
Uniprot IDQ8R183
Protein RefSeqNP_599010.4
mRNA RefSeqNM_134249.5

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