Rat Anti-Mouse IL-23 receptor

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Cat-Nr.103-M251
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#6D34)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-23R extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
AntigenMouse recombinant EC domain of IL-23 R
ApplicationWB
SynonymsIl23r; IL-23R
DescriptionThe functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the IL-23-specific receptor subunit (IL-23 R). IL-23 R shares structural features with the IL-12 R beta 2, including an N-terminal Ig-like domain, two cytokine receptor domains and multiple glycosylation sites in the extracellular domain. IL-23 R lacks the three extracellular membrane-proximal fibronectin-type III domains present on IL-12 R beta 2.
Uniprot IDQ8K4B4
Protein RefSeqNP_653131.2
mRNA RefSeqNM_144548.1

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