Mouse Anti-Human TNFSF13B

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Cat-Nr.101-M675
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#8K16)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of the extracellular domain of TNFSF13B (also called BAFF).
AntigenHuman recombinant TNFSF13B (EC domain)
ApplicationWB, FC
SynonymsTNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
DescriptionBAFF (B cell activating factor), also known as BlyS (B lymphocyte stimulator) and TALL-1 (TNF- and APOL-related leukocyte expressed ligand 1) is a member of the TNF superfamily designated TNFSF13B. BAFF is expressed by monocytes and dendritic cells in the form of a membrane-anchored homotrimer which may be shed from the cell surface by Furin. BAFF binds BAFF R/TNFRSF13C, BCMA/TNFRSF17 and TACI/TNFRSF13B receptors to regulate B cell homeostasis.
Uniprot IDQ9Y275
Protein RefSeqNP_006564.1
mRNA RefSeqNM_006573.4

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