Mouse Anti-Human TNFSF12

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Cat-Nr.101-M673
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#10T24)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human TNFSF12 recombinant protein.
Antigenhuman recombinant TNFSF12
ApplicationWB
SynonymsTNFSF12; APO3L; DR3LG; TWEAK
DescriptionTWEAK is a type II transmembrane protein belonging to the TNF superfamily. The extracellular domains of human and mouse TWEAK share 89% amino acid sequence identity. A soluble form of TWEAK is generated from the membrane-associated molecule by proteolytic cleavage after Arg 93, suggesting that TWEAK may have long-range effects. TWEAK is expressed widely in many tissues and cells.
Uniprot IDO43508
Protein RefSeqNP_003800.1
mRNA RefSeqNM_003809.2

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