Mouse Anti-Human TRAIL/Apo2L

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Size500 µg
Price250 €
CategoryMonoclonal Antibody
IsotypeIgG1, kappa
Species ReactivityHuman
Formulationlyophilized from PBS
ReconstitutionReconstitute the antibody in sterile water to a concentration of 1.0mh/mL.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced in BALB/c x ICR F1 mice using highly pure (>98%) recombinant human TRAIL/APO2L as the immunizing antigen. This IgG1K antibody was purified from ascites fluid by Protein A affinity chromatography.
AntigenRecombinant human TRAIL/ApoL2
SynonymsTNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L
DescriptionTNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.
Uniprot IDP50591
Protein RefSeqNP_003801.1
mRNA RefSeqNM_003810.3

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