Mouse Anti-Human Trk-A

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Cat-Nr.101-M688
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#8X5)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human Trk-A recombinant protein.
Antigenhuman recombinant Trk-A
ApplicationWB
SynonymsNTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
DescriptionTrkA, the product of the protooncogene trk, is a member of the neurotrophic tyrosine kinase receptor family that has three members. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a conserved complex subdomain organization consisting of a signal peptide, two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains in the extracellular region, as well as an intracellular region that contains the tyrosine kinase domain.
Uniprot IDP04629
Protein RefSeqNP_001012331
mRNA RefSeqNM_001012331

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