Rat Anti-Mouse TREM-2b

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Cat-Nr.103-M280
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#5J46)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of the EC-domain of TREM-2b.
Antigenrecombinant mouse extracellular domain of TREM-2b
ApplicationWB
SynonymsTrem2; Trem2a; Trem2b; Trem2c
DescriptionTREM2 is a single Ig domain receptor expressed by cells of myeloid lineage. Two closely related transcripts were reported in mouse and designated TREM2a and TREM2b. TREM2 is a pattern recognition receptor that binds anionic ligands. It associates with the adapter protein DAP12 to deliver an activating signal that plays a role in both innate and adaptive immune responses.
Uniprot IDQ99NH8
Protein RefSeqNP_112544
mRNA RefSeqNM_031254

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