Mouse Anti-Human TMEFF1

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Cat-Nr.101-M650
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#7S12)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of Human Transmembrane protein wth EGF-like and two Follistatin-like domains (TMEFF1), also called Tomoregulin-1.
AntigenEC domain of human TMEFF1 (also called Tomoregulin-1)
ApplicationWB
SynonymsTMEFF1; TR-1; H7365; C9orf2; CT120.1
DescriptionTransmembrane Protein with EGF-like and two Follistatin-like domains 1 (TMEFF1) also known as tomoregulin-1 is a type I transmembrane glycoprotein. TMEFF1 contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain of TMEFF1 can be released as a soluble protein. TMEFF1 is predominantly expressed in brain, but is downregulated in brain neoplasms. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.
Uniprot IDQ8IYR6
Protein RefSeqNP_003683.2
mRNA RefSeqNM_003692.4

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