Mouse Anti-Human TROP-2

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Cat-Nr.101-M691
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#49D6)
IsotypeIgG2A
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human TROP-2 recombinant protein.
Antigenhuman recombinant TROP-2
ApplicationWB, FC
SynonymsTACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
DescriptionHuman TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), gp50 and T16, is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It is related to EpCAM, also called TROP-1, gp40 and KSA. A study of these two genes suggests that TROP-2 was generated through the retropositioning of the EpCAM gene. TROP-2 and EpCAM share approximately 49% amino acid sequence identity and approximately 67% similarity. Mature human and mouse TROP-2 share 80% amino acid identity.
Uniprot IDP09758
Protein RefSeqNP_002344
mRNA RefSeqNM_002353

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