Rat Anti-Mouse Serpin C1

Slide this table

Cat-Nr.103-M468
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#10D37)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of Serpin C1 (also called antithrombin III).
Antigenrecombinant mouse Serpin-C1
ApplicationWB
SynonymsSerpinc1; At3; At-3; ATIII; AI114908
DescriptionThe human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.
Uniprot IDP32261
Protein RefSeqNP_543120.1
mRNA RefSeqNM_080844.4

All prices plus VAT + possible delivery charges