Mouse Anti-Human PIN

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Cat-Nr.101-M606
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#9S2)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with recombinant human PIN.
Antigenrecombinant human PIN
ApplicationWB
SynonymsPIN1; DOD; UBL5
DescriptionPin1 is a peptidylprolyl isomerase (PPI) that targets phosphorylated Ser or Thr residues followed by a Pro (S/TP). Isomerization of phosphorylated Ser or Thr residues may alter protein confirmation and, subsequently, modify activity. Pin1 is overexpressed in many human breast cancers, and has been shown to modify numerous proteins including p53,NFκB, cJun, cyclin D1, and βcatenin.
Uniprot IDQ13526
Protein RefSeqNP_006212.1
mRNA RefSeqNM_006221.3

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