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    Rabbit Anti-Human BD-5 NEW

    Size:
    100 µg
    Price:
    € 235
    Formulation:
    Polyclonal Antibody ; lyophilized
    Catalog Number:
    102-P99
    Synonyms:
    BD5, DEFB5, DEFB105a, Beta-Defensin 5
    Application:
    ELISA, WB
    Antigen:
    E.coli derived Recombinant Human BD-5
    Stability:
    The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
    Reconstitution:
    Reconstitute in sterile water to a concentration of 0.1-1.0mg/mL.
    Description:
    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
    NCBI Gene ID:
    245908
    Uniprot:
    Q8NG35
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