Human Eotaxin (CCL11) (Animal Free)

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Cat-Nr.100-448S-AF
Size5 µg
Price135 €
SourceE. coli
Formulationlyophilized
Purity Confirmation≥ 98% by SDS-PAGE gel and HPLC analyses.
Length [aa]74
Molecular Weight8.3 kDa
Endotoxin Levels< 0.01 ng/µg of protein (< 0.1 EU/µg)
Biological ActivityNot available.
Species ReactivityHuman
SynonymsCCL11
DescriptionEotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Protein SequenceGPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP
Uniprot IDP51671
Protein RefSeqNP_002977.1
mRNA RefSeqNM_002986.2

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