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    Mouse IL-28B NEW

    Host:
    E. coli
    Size:
    20 µg
    Price:
    € 170
    Formulation:
    lyophilized
    Catalog Number:
    M10-039
    Synonyms:
    Interferon lambda-3, IFN-lambda-3, Interleukin-28B, IL-28B, Ifnl3, Il28, Il28b
    Purity Confirmation:
    > 97% by SDS-PAGE & HPLC analyses
    Biological activity:
    The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 30 ng/ml, corresponding to a specific activity of > 3.3 × 104 IU/mg.
    Stability:
    Lyophilized IL-28B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C.
    Reconstitution:
    It is recommended to reconstitute the lyophilized IL-28B in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
    Protein Sequence:
    DPVPRATRLP VEAKDCHIAQ FKSLSPKELQ AFKKAKGAIE KRLLEK DMRC SSHLISRAWD LKQLQVQERP KALQAEVALT LKVWENINDS A LTTILGQPL HTLSHIHSQL QTCTQLQATA EPKPPSRRLS RWLHRLQ EAQ SKETPGCLED SVTSNLFQLL LRDLKCVASG DQCV
    Description:
    IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
    NCBI Gene ID:
    338374
    Uniprot:
    Q8CGK6
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