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    Mouse IL-12p40 NEW

    Host:
    HEK 293 cells
    Size:
    2 µg
    Price:
    € 75
    Formulation:
    lyophilized
    Catalog Number:
    100-027S
    Synonyms:
    Interleukin-12, NKSF, CTL Maturation Factor (TCMF), Cytotoxic Lymphocyte Maturation Factor (CLMF),TSF,, p40:Interleukin-12 subunit beta, IL-12 subunit p40, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit(CLMF p40), NK cell Stimulating Factor Chain 2
    Purity Confirmation:
    > 95% by SDS-PAGE & HPLC analyses
    Biological activity:
    Determined by its ability to inhibit the proliferative effect of 2 ng/ml mIL-12p70 in T-cell enriched PBMCs.
    Protein Sequence:
    MWELEKDVYV VEVDWTPDAP GETVNLTCDT PEEDDITWTS DQRHGV IGSG KTLTITVKEF LDAGQYTCHK GGETLSHSHL LLHKKENGIW S TEILKNFKN KTFLKCEAPN YSGRFTCSWL VQRNMDLKFN IKSSSSS PDS RAVTCGMASL SAEKVTLDQR DYEKYSVSCQ EDVTCPTAEE TL PIELALEA RQQNKYENYS TSFFIRDIIK PDPPKNLQMK PLKNSQVE VS WEYPDSWSTP HSYFSLKFFV RIQRKKEKMK ETEEGCNQKG AFL VEKTSTE VQCKGGNVCV QAQDRYYNSS CSKWACVPCR VRS
    Description:
    IL-12 is a potent regulator of cell-mediated immune responses and it induces IFN-γ production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue-type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells, and induces the development of IFN-γ-producing Th1 cells. Recombinant Murine IL-12p40 is a 40.0 kDa protein consisting of 313 amino acid residues and less than 5%of the IL-12p80 dimer.
    NCBI Gene ID:
    16160
    Uniprot:
    P43432
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