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    Human HPRG NEW

    Host:
    CHO cells
    Size:
    5 µg
    Price:
    € 75
    Formulation:
    lyophilized
    Catalog Number:
    100-439S
    Synonyms:
    Histidine-Proline-Rich Glycoprotein, Histidine-rich glycoprotein (HRG), HRGP, THPH11
    Purity Confirmation:
    > 90% by SDS-PAGE & HPLC analyses
    Biological activity:
    Measured by its ability to support adhesion of Con-A activated MOLT-4 cells to the Recombinant Human HPRG-coated surface. The ED50 for this effect is 1.5-2.0 μg/ml.
    Protein Sequence:
    VSPTDCSAVE PEAEKALDLI NKRRRDGYLF QLLRIADAHL DRVENT TVYY LVLDVQESDC SVLSRKYWND CEPPDSRRPS EIVIGQCKVI A TRHSHESQD LRVIDFNCTT SSVSSALANT KDSPVLIDFF EDTERYR KQA NKALEKYKEE NDDFASFRVD RIERVARVRG GEGTGYFVDF SV RNCPRHHF PRHPNVFGFC RADLFYDVEA LDLESPKNLV INCEVFDP QE HENINGVPPH LGHPFHWGGH ERSSTTKPPF KPHGSRDHHH PHK PHEHGPP PPPDERDHSH GPPLPQGPPP LLPMSCSSCQ HATFGTNGA Q RHSHNNNSSD LHPHKHHSHE QHPHGHHPHA HHPHEHDTHR QHPH GHHPHG HHPHGHHPHG HHPHGHHPHC HDFQDYGPCD PPPHNQGHCC HGHGPPPGHL RRRGPGKGPR PFHCRQIGSV YRLPPLRKGE VLPLP EANFP SFPLPHHKHP LKPDNQPFPQ SVSESCPGKF KSGFPQVSMF FTHTFPK
    Description:
    Histidine-proline-rich glycoprotein (HPRG), a member of the Cystatin structural superfamily, is an abundantly secreted multi-domain glycoprotein. Although the physiological function is largely unknown, HPRG potentially regulates physiological processes such as cell adhesion and migration, fibrinolysis, coagulation, complement activation, immune complex clearance and phagocytosis of apoptotic cells. HPRG can exert anti-angiogneic activity by stimulating apoptosis of endothelial cells. Recombinant Human HPRG is a 57.7 kDa glycoprotein containing 507 amino acid residues.
    NCBI Gene ID:
    3273
    Uniprot:
    P04196
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