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    Human FGF-8a NEW

    Host:
    CHO cells
    Size:
    5 µg
    Price:
    € 75
    Formulation:
    lyophilized
    Catalog Number:
    100-438S
    Synonyms:
    Fibroblast Growth Factor-8, FGF-8a, AIGF, HBGF-8
    Purity Confirmation:
    > 95% by SDS-PAGE & HPLC analyses
    Biological activity:
    Determined by a cell proliferation assay using balb/c 3T3 cells.
    Protein Sequence:
    QHVREQSLVT DQLSRRLIRT YQLYSRTSGK HVQVLANKRI NAMAED GDPF AKLIVETDTF GSRVRVRGAE TGLYICMNKK GKLIAKSNGK G KDCVFTEIV LENNYTALQN AKYEGWYMAF TRKGRPRKGS KTRQHQR EVH FMKRLPRGHH TTEQSLRFEF LNYPPFTRSL RGSQRTWAPE PR
    Description:
    FGF-8 is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8a, FGF-8b, FGF-8e and FGF-8f. The human and murine FGF-8a and FGF-8b are identical, unlike human and mouse FGF-8e and FGF-8f, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. CHO cell-derived recombinant human FGF-8a is a 21.2 kDa protein consisting of 182 amino acid residues.
    NCBI Gene ID:
    2253
    Uniprot:
    P55075-2
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