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    Rat Anti-Mouse TIE-2, agonistic

    Size:
    200 µg
    Price:
    € 390
    Formulation:
    Monoclonal Antibody ; lyophilized
    Clone/AB feature:
    (#MAB1201)
    Isotype:
    IgG2
    Catalog Number:
    mT1002r-m
    Synonyms:
    Angiopoietin-1 receptor; Endothelial tyrosine kinase; HYK; STK1; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; p140 TEK; CD202b; Tek; Hyk; Tie2; AA517024
    Application:
    WB, Activation
    Antibody generation:
    This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse extracellular domain of Tie2 receptor. The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized.
    Antigen:
    Mouse Tie2 extracellular domain
    Stability:
    Lyophilized samples are stable for 2 years from date of receipt when stored at -70 °C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
    Reconstitution:
    Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 400 µg/ml.
    Description:
    Tie-2 is an endothelial-specific receptor tyrosine kinase and a receptor for angiopoietins. Tie-2 is predominantly expressed in the endothelium and it is likely involved in the regulation of vascular maturation and stability.
    NCBI Gene ID:
    21687
    Uniprot:
    Q02858
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