Monoclonal Antibody ; lyophilized
Angiopoietin-1 receptor; Endothelial tyrosine kinase; HYK; STK1; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; p140 TEK; CD202b; Tek; Hyk; Tie2; AA517024
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse extracellular domain of Tie2 receptor. The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized.
Mouse Tie2 extracellular domain
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 °C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 400 µg/ml.
Tie-2 is an endothelial-specific receptor tyrosine kinase and a receptor for angiopoietins. Tie-2 is predominantly expressed in the endothelium and it is likely involved in the regulation of vascular maturation and stability.
NCBI Gene ID: