Monoclonal Antibody ; lyophilized
NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human Trk-A recombinant protein.
human recombinant Trk-A
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
TrkA, the product of the protooncogene trk, is a member of the neurotrophic tyrosine kinase receptor family that has three members. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a conserved complex subdomain organization consisting of a signal peptide, two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains in the extracellular region, as well as an intracellular region that contains the tyrosine kinase domain.
NCBI Gene ID: