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    Mouse Anti-Human KIR2DS4

    Size:
    100 µg
    Price:
    € 250
    Formulation:
    Monoclonal Antibody ; lyophilized
    Clone/AB feature:
    (#2G42)
    Isotype:
    IgG2
    Catalog Number:
    101-M542
    Synonyms:
    KIR2DS4; KKA3; KIR1D; NKAT8; CD158I; KIR412
    Application:
    WB, FC
    Antibody generation:
    This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of KIR2DS4.
    Antigen:
    human recombinant KIRDS4
    Stability:
    Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
    Reconstitution:
    Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
    Description:
    The KIR gene family currently consists of 15 gene loci (KIR2DL1, KIR2DL2/L3, KIR2DL4, KIR2DL5A, KIR2DL5B, KIR2DS1, KIR2DS2, KIR2DS3, KIR2DS4, KIR2DS5, KIR3DL1/S1, KIR3DL2, KIR3DL3 and two pseudogenes, KIR2DP1 and KIR3DP1) encoded within a 100-200 Kb region of the Leukocyte Receptor Complex (LRC) located on chromosome 19 (19q13.4). The LRC constitutes a large, 1 Mb, and dense cluster of rapidly evolving immune genes which contains genes encoding other cell surface molecules with distinctive Ig-like extra-cellular domains. These genes include, from centromere to telomere, Leukocyte Immunoglobulin-like Receptors (LILR) and Leukocyte-Associated Immunoglobulin-like Receptors (LAIR), FcGammaR as well as the Natural cytotoxicity-triggering Receptor 1 (NCR1). In addition the extended LRC contains genes encoding the Sialic acid binding Immunoglobulin-like Lectins (SIGLEC) and the CD66 family members such as the carcino-embryonic antigen (CEA) genes as well as the genes encoding the transmembrane adaptor molecules DAP10 and DAP12.
    NCBI Gene ID:
    3809
    Uniprot:
    P43632
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