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    Mouse Anti-Human Kallikrein 7

    Size:
    100 µg
    Price:
    € 250
    Formulation:
    Monoclonal Antibody ; lyophilized
    Clone/AB feature:
    (#5J28)
    Isotype:
    IgG2
    Catalog Number:
    101-M533
    Synonyms:
    KLK7; hK7; SCCE; PRSS6
    Application:
    WB, N
    Antibody generation:
    This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Kallikrein-7.
    Antigen:
    human recombinant Kallikrein-7
    Stability:
    Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
    Reconstitution:
    Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
    Description:
    The human tissue kallikrein (KLK) gene family contains 15 members that play important roles in cancer. Notably, kallikrein-1, also known as tissue kallikrein, cleaves kininogen to release the vasoactive kinin peptide, bradykinin or lysyl-bradykinin. Kallikrein-3, called prostate specific antigen (PSA), is an established tumor marker that aids in the diagnosis, staging, and follow up of prostate cancer. Kallikrein-4 is specifically expressed in the prostate and over-expressed in prostate cancer. Kallikrein-5 is widely expressed but found at high levels in skin, breast, brain and testis; over-expression is an indicator of poor prognosis in ovarian cancer. Kallikrein-8 is expressed in the brain and is a novel marker of ovarian and cervical cancer.
    NCBI Gene ID:
    5650
    Uniprot:
    P49862
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